By Inge Scharrer, Wolfgang Schramm
This publication comprises the contribution to the thirty fifth Hemophilia Symposium, Hamburg 2004. the most themes are epidemiology, chance of infections and inhibitors in hemophilia, persistent hemophilic synovitis and long term result of orthopedic therapy, laboratory diagnostics and pediatric hemostaseology. the quantity is rounded off via various unfastened papers and posters on hemophilia and hemorrhagic issues and inhibitors in hemophilia.
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Extra info for 35th Hemophilia Symposium Hamburg 2004: Epidemiology;Risk of Infections and Inhibitors in Hemophilia; Chronic lic Synovitis and Long-term Results of Orthopedic ... Hemostaseology;Free Lectures
Health Canada was the first agency to respond to the issue, focusing on imported factor XI and issued a statement on October 18th that »the grounds for action related to potential secondary transmission are theoretical. The Steering Committee of Infection Control 32 P. L. F. « Of course, the United Kingdom has been the principal country affected by BSE but it is by no means the only affected country. BSE has been reported in a significant number of cattle in several other European countries and furthermore potentially contaminated food product (bone meal) for cattle was exported to many countries around the world from the UK at the height of the BSE epidemic.
The small numbers in each category hardly admit interpretation, all the less with 7 deaths of unknown origin. Some tendencies seem to become apparent: 1. HIV associated deaths are not dominant (we have to recall that registration started in 1996), 2. the most imminent causes of death are bleedings (7 patients) – of all localizations and independent of the inhibitor status – and chronic liver disease (7 patients), including 3 liver cirrhosis and 3 liver cancer, the latter increasing over the last 4 years.
In the 2003/2004 survey, a total number of 8445 patients (including possible double registrations) have been reported from the participating centers. Results Participating centers Since the first survey the number of participating centers has increased every year with a particularly rise in 1991 when the hemophilia treatment centers of the former East Germany joined in. Today these centers contribute a significant portion of the overall data (Fig. 1). In the last years’ surveys the number of reporting centers persisted relatively constant.